Search on: FK506-BINDING PROTEIN 1A 
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Descriptor English:   Tacrolimus Binding Protein 1A 
Descriptor Spanish:   Proteína 1A de Unión a Tacrolimus 
Descriptor Portuguese:   Proteína 1A de Ligação a Tacrolimo 
Synonyms English:   FK506-Binding Protein 1
FKBP-12
Macrophilin-12
FK506 Binding Protein 1
FK506 Binding Protein 1A
FKBP 12
Macrophilin 12
FK506-Binding Protein 1A
FKBP12  
Tree Number:   D08.811.399.325.500.400.700.500
D12.776.543.750.705.400.700.500
D12.776.827.275.700.500
Definition English:   A 12-KDa tacrolimus binding protein that is found associated with and may modulate the function of calcium release channels. It is a peptidyl-prolyl cis/trans isomerase which is inhibited by both tacrolimus (commonly called FK506) and SIROLIMUS. 
History Note English:   2001; use TACROLIMUS BINDING PROTEINS (NM) 1991-2000 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   35327 
Unique Identifier:   D022061 

Occurrence in VHL:
 

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